Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
-
Reference Standards Related Products (11493)
Related Products (11493)
-
BMS-986142 (Standard)
0 ImagesCat. No.: HY-101856RCAS No.: 1643368-58-4BMS-986142 (Standard) is the analytical standard of BMS-986142 (HY-101856). This product is intended for research and analytical applications. BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.
-
VPC 23019 (Standard)
0 ImagesCat. No.: HY-108490RCAS No.: 449173-19-7VPC 23019 (Standard) is the analytical standard of VPC 23019 (HY-108490). This product is intended for research and analytical applications. VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
-
CMF019 (Standard)
0 ImagesCat. No.: HY-103080RCAS No.: 1586787-08-7CMF019 (Standard) is the analytical standard of CMF019 (HY-103080). This product is intended for research and analytical applications. CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension.
-
(±)-10-Hydroxycamptothecin (Standard)
0 ImagesCat. No.: HY-N0275RCAS No.: 64439-81-2Synonyms: (±)-10-HCPT (Standard)(±)-10-Hydroxycamptothecin (Standard) is the analytical standard of (±)-10-Hydroxycamptothecin. This product is intended for research and analytical applications. (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.
-
Cipralisant (Standard)
0 ImagesCat. No.: HY-106993RCAS No.: 213027-19-1Synonyms: GT-2331 (Standard)Cipralisant (Standard) (GT-2331 (Standard)) is the analytical standard of Cipralisant (HY-106993). This product is intended for research and analytical applications. Cipralisant (GT-2331) is an orally active, low-toxicity, potent, selective, high affinity histamine H3 receptor full antagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47 nM for rat histamine H3 receptor. Cipralisant has the potential for attention-deficit hyperactivity disorder research. Cipralisant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
Sinefungin (Standard)
0 ImagesCat. No.: HY-101938RCAS No.: 58944-73-3Synonyms: Adenosyl-Ornithine (Standard); A-9145 (Standard); Antibiotic 32232RP (Standard)Sinefungin (Standard) is the analytical standard of Sinefungin (HY-101938). This product is intended for research and analytical applications. Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.
-
cis-Verbenol (Standard)
0 ImagesCat. No.: HY-W674037RCAS No.: 18881-04-4cis-Verbenol (Standard) is the analytical standard of cis-Verbenol (HY-W674037). This product is intended for research and analytical applications. cis-Verbenol is a sex pheromone capable of inhibiting aggregation and inducing dispersion of mountain pine beetles (Dendroctonus ponderosae Hopkins) and can be isolated from pine engravers.
-
Laduviglusib monohydrochloride (Standard)
0 ImagesSynonyms: CHIR-99021 monohydrochloride (Standard); CT99021 monohydrochloride (Standard)Laduviglusib (monohydrochloride) (Standard) is the analytical standard of Laduviglusib (monohydrochloride). This product is intended for research and analytical applications. Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy.
-
Vitexin-2"-O-rhamnoside (Standard)
0 ImagesCat. No.: HY-N0534RCAS No.: 64820-99-1Vitexin-2"-O-rhamnoside (Standard) is the analytical standard of Vitexin-2"-O-rhamnoside (HY-N0534). This product is intended for research and analytical applications. Vitexin-2"-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2"-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2"-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC50 of 17.5 μM. Vitexin-2"-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2"-O-rhamnoside has antioxidant activity. Vitexin-2"-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases.
-
Ketoprofen impurity 1 (Standard)
0 ImagesCat. No.: HY-W104310RCAS No.: 320730-08-33-(2-Hydroxyethyl)benzoic acid (Standard) is the analytical standard of 3-(2-Hydroxyethyl)benzoic acid. This product is intended for research and analytical applications.
-
Apitolisib (Standard)
0 ImagesSynonyms: GDC-0980 (Standard); GNE 390 (Standard); RG 7422 (Standard)Apitolisib (Standard) is the analytical standard of Apitolisib. This product is intended for research and analytical applications. Apitolisib (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC50s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with a Ki of 17 nM for mTOR.
-
MX69 (Standard)
0 ImagesCat. No.: HY-100892RCAS No.: 1005264-47-0
-
Lys-SMCC-DM1 (Standard)
0 ImagesCat. No.: HY-101982RCAS No.: 1281816-04-3Synonyms: Lys-Nε-MCC-DM1 (Standard)Lys-SMCC-DM1 (Standard) is the analytical standard of Lys-SMCC-DM1 (HY-101982). This product is intended for research and analytical applications. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer.
-
Cinoxacin (Standard)
0 ImagesCat. No.: HY-B1085RCAS No.: 28657-80-9Synonyms: Compound 64716 (Standard)Cinoxacin (Standard) is the analytical standard of Cinoxacin. This product is intended for research and analytical applications. Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.
-
Gingerenone A (Standard)
0 ImagesGingerenone A (Standard) is the analytical standard of Gingerenone A. This product is intended for research and analytical applications. Gingerenone A is an Nrf2-Gpx4 activator that can induce Ferroptosis in liver damage with oral activity. Gingerenone A has anti-inflammatory, anti-diabetic, anti-tumor, and pro-aging effects in mice.
-
Ripasudil (Standard)
0 ImagesSynonyms: K-115 (Standard)
-
Oxatomide (Standard)
0 ImagesCat. No.: HY-123205RCAS No.: 60607-34-3Synonyms: KW-4354 (Standard)Oxatomide (Standard) (KW-4354 (Standard)) is the analytical standard of Oxatomide (HY-123205). This product is intended for research and analytical applications. Oxatomide (KW-4354) is an orally active dual antagonist of the H1-histamine receptor and the P2X7 receptor, as well as an inhibitor of serotonin. Oxatomide possesses antihistaminic, antiallergic and anti-inflammatory activities. Oxatomide can be used in the research of allergic diseases.
-
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard)
0 ImagesCat. No.: HY-103608RCAS No.: 1835705-61-7Synonyms: VHL Ligand-Linker Conjugates 11 (Standard); E3 ligase Ligand-Linker Conjugates 11 (Standard)(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-(C3-PEG)2-C6-Cl (HY-103608). This product is intended for research and analytical applications. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.
-
Methazolamide (Standard)
0 ImagesMethazolamide (Standard) is the analytical standard of Methazolamide. This product is intended for research and analytical applications. Methazolamide (L584601) is a BBB-penetrable and orally active carbonic anhydrase inhibitor, with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide can reduce intraocular pressure and has a neuroprotective effect, being able to inhibit neuronal apoptosis. Methazolamide can be used in the research of ophthalmic diseases such as glaucoma and cerebrovascular diseases such as subarachnoid hemorrhage.
-
Galanthaminone (Standard)
0 ImagesSynonyms: (-)-Narwedine (Standard); Narwedin (Standard)Galanthaminone (Standard) is the analytical standard of Galanthaminone. This product is intended for research and analytical applications. Galanthaminone (Narwedin) is a competitive and reversible cholinesterase (AChE) inhibitor; is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
